Meydan Lab › Research evidence
Research funding and collaborations
Dr. Cem Meydan has contributed to competitively funded research programs across chromatin biology, blood cancers, cancer disparities, single-cell and spatial multi-omics, viral and microbial genomics, and spaceflight biology. His roles include co-investigator and key personnel, alongside computational research collaborations supported by the NIH, Blood Cancer United (formerly the Leukemia & Lymphoma Society), Cancer Grand Challenges, NASA, and other funders. Together, these programs demonstrate sustained experience in computational research across institutions, disciplines, and translational settings.
These are collaborative awards. Each entry identifies the program’s principal investigators and Dr. Meydan’s role separately. Historical participation predating the Meydan Lab is included for research context.
This is a selected list rather than a complete record of Dr. Meydan’s funded collaborations, and the outputs under each program are representative examples rather than full bibliographies. Further programs and publications may be added as records are reviewed.
Research areas and role attribution
- Cancer epigenetics and gene regulation: BAF/SWI-SNF biology, chromatin looping, B-cell states, and lymphoma therapeutic vulnerabilities.
- Computational and spatial multi-omics: integrative genomics, single-cell and spatial analysis, and molecular characterization across tissues and patient cohorts.
- Infection, microbiome, and virome biology: computational profiling of microbial and viral communities, host responses, and diagnostic assays.
- Spaceflight and systems biology: genomic and epigenomic analyses of molecular responses to spaceflight and environmental stress.
How grant roles and sources are documented
Grant roles follow Dr. Meydan’s professional funding records. Weill Cornell publicly lists his key-personnel role on SAMBAI. Many other public funder records name the award investigators but do not enumerate all co-investigators, key personnel, or scientific contributors.
A program principal investigator leads the named award. Participation in a project, subaward, or shared core does not imply responsibility for the full center budget or award administration.
Multiple cores within one center are grouped under their parent program. Award periods describe the funder’s project dates; individual participation periods are provided separately where they differ. Sources include official award records and publication acknowledgments, with archived copies (Internet Archive Wayback Machine or archive.today) when available.
Selected outputs include only publications coauthored by Dr. Meydan and research resources from the same studies. “Acknowledges” means the paper names that grant in its funding or acknowledgment statement; a paper may acknowledge several awards. Research tools and data portals are attributed to their development teams.
Additional formats: Markdown record · structured data.
Recent and multi-year funded programs
Programs with project periods extending into 2026 or later.
SAMBAI: cancer inequities in populations of African descent
- Funder
- Cancer Grand Challenges (Cancer Research UK and the U.S. National Cancer Institute)
- Program
- SAMBAI — Social, Ancestry, Molecular and Biological Analysis of Inequalities
- Award period
- Funded in 2024. Weill Cornell lists 2024–2029 (Cancer Research UK channel) and 2024–2026 (NCI channel).
- Principal investigators
- Melissa B. Davis (team lead, Morehouse School of Medicine)
- Dr. Meydan’s role
- Key personnel
SAMBAI combines large-scale genomic, molecular, environmental, and social data to investigate cancer inequities in populations of African descent. As key personnel, Dr. Meydan contributes computational expertise to molecular characterization and the development of analytical approaches for population-specific cancer research.
SAMBAI launched in 2024 and is in its data-generation phase; publications from the program are forthcoming.
The two Weill Cornell funding entries are channels within a single SAMBAI research initiative.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| SAMBAI Cancer Grand Challenges | The team, its lead, year funded and research aims. | Wayback Machine |
| Cancer Grand Challenges funding awarded to study cancer inequity Weill Cornell Medicine Newsroom | Weill Cornell’s participation in the 2024 award. | Wayback Machine |
| Cem Meydan — faculty profile, Research section Weill Cornell VIVO | Dr. Meydan listed as key personnel on SAMBAI under Cancer Research UK (2024–2029) and the National Cancer Institute (2024–2026). | Wayback Machine |
Lymphoma SPORE: addressing health disparities in lymphoma
- Funder
- NIH / National Cancer Institute
- Program
- Lymphoma Outcomes SPORE (Weill Cornell title: SPORE: Addressing Health Disparities in Lymphoma)
- Award number
- U54CA302435
- Award period
- August 2025 – July 2030 (NIH RePORTER; Weill Cornell record).
- Principal investigators
- Christopher R. Flowers (contact PI) and Jean L. Koff, MD Anderson Cancer Center. Weill Cornell subaward: Ari M. Melnick (co-principal investigator; leads Project 1) and Roberta Zappasodi (subaward principal investigator).
- Dr. Meydan’s role
- Computational research collaborator
The NCI Lymphoma Outcomes SPORE integrates tumor biology, clinical data, and population-level evidence to investigate disparities in lymphoma outcomes. Within the Weill Cornell research effort, Dr. Meydan contributes computational expertise to studies of B-cell states, immune signaling, and chromatin–microenvironment interactions, with an emphasis on biologically informed therapeutic vulnerabilities.
Selected outputs · 1 coauthored publication
- The LMO2–LDB1–TAL1 complex regulates transcription networks in acute myeloid leukemia (2025) · Acknowledges U54CA302435
Coauthored study of the transcriptional networks of acute myeloid leukemia.
Components of this program
- Project 1: Precision targeting of therapeutic vulnerabilities specific to African American lymphoma patients. Led by Ari M. Melnick (NIH RePORTER subproject listing).
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Lymphoma Outcomes SPORE, U54CA302435 NIH RePORTER | Award number, principal investigators, project dates, projects and cores. | Wayback Machine |
| SPORE: Addressing Health Disparities in Lymphoma (Weill Cornell subaward) Weill Cornell VIVO | Weill Cornell subaward of U54CA302435, 2025–2030, and its Weill Cornell investigators. | Wayback Machine |
| Christopher Flowers, MD MD Anderson Cancer Center | The program’s contact principal investigator. | Wayback Machine |
Epigenetic mechanisms and targeting in hematological malignancy
- Funder
- Blood Cancer United (formerly the Leukemia & Lymphoma Society)
- Program
- Epigenetic Mechanisms and Targeting in Hematological Malignancy — Specialized Center of Research (SCOR)
- Award period
- October 2024 – September 2029 (Blood Cancer United).
- Principal investigators
- Jonathan D. Licht (center principal investigator). Project 1, on chromatin looping in B-cell lymphoma, is led by Ari M. Melnick.
- Dr. Meydan’s role
- Computational genomics collaborator
This Blood Cancer United SCOR investigates epigenetic dysregulation and therapeutic vulnerabilities in hematologic malignancies. Dr. Meydan’s work within the lymphoma chromatin-looping effort applies computational approaches to CTCF, PDS5B, and loop extrusion, linking genome organization with B-cell gene regulation.
This center continues an earlier Leukemia & Lymphoma Society SCOR led by Dr. Licht (2019–2024, listed under Cancer research and translational programs). The two award cycles are separate entries.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Epigenetic Mechanisms and Targeting in Hematological Malignancy Blood Cancer United | Project term, center principal investigator and the five project descriptions, including Project 1 on DNA looping. | Wayback Machine |
| Jonathan Licht, MD Blood Cancer United | Dr. Licht as principal investigator of the SCOR program. | Not yet archived |
VAST Center: Viromes Across Space(s) and Time
- Funder
- NIH Common Fund, Human Virome Program (administered by the National Institute on Aging)
- Program
- VAST Center: Viromes Across Space(s) and Time — Human Virome Characterization Center
- Award number
- U54AG089334
- Award period
- February 2025 – January 2030 (NIH RePORTER).
- Principal investigators
- Michael P. Snyder (contact PI), Ami S. Bhatt and Christopher E. Mason; led from Stanford University.
- Dr. Meydan’s role
- Computational and multi-omics collaborator
The NIH-funded VAST Center characterizes the human virome across people, body sites, environments, and time using longitudinal samples and molecular profiling. Dr. Meydan contributes computational and multi-omic research expertise to this multi-institutional effort, extending his work at the intersection of microbial genomics and human molecular biology.
The VAST Center launched in 2025 and is in its initial sample-collection and data-generation phase; center publications are forthcoming. An early coauthored study acknowledging the award is listed below.
Selected outputs · 1 coauthored publication
- Systemic elevation of gut-derived p-cresol during one year in space (2026) · Acknowledges U54AG089334
Coauthored longitudinal metabolomic study from the NASA Twins Study.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Human Virome Program — Funded Research NIH Common Fund | The VAST Center among the funded Human Virome Characterization Centers, with its principal investigators. | Wayback Machine |
| VAST Center, U54AG089334 NIH RePORTER | Award number, principal investigators, institution and project dates. | Wayback Machine |
| Stanford Medicine awarded grant to study viral community in humans Stanford Medicine News Center | Center launch (May 2025), aims and principal investigators. | Wayback Machine |
The immune niche in the development of hematological malignancies
- Funder
- Blood Cancer United (formerly the Leukemia & Lymphoma Society)
- Program
- The Immune Niche in the Development of Hematological Malignancies and Implications for Novel Therapy — Specialized Center of Research (SCOR)
- Award number
- LLS 7029-22 (Weill Cornell subaward for the single-cell core)
- Award period
- October 2022 – September 2027 (Blood Cancer United; Weill Cornell record).
- Principal investigators
- Tak W. Mak (center principal investigator, Princess Margaret Cancer Centre). At Weill Cornell: Christopher E. Mason (core lead and subaward principal investigator) and Ari M. Melnick (Project 2 lead).
- Dr. Meydan’s role
- Key personnel, in two components of the same program
This Blood Cancer United SCOR investigates how the immune and stromal environment shapes hematologic malignancies and creates treatment opportunities. As key personnel in its Weill Cornell components, Dr. Meydan contributes single-cell, spatial, and integrative computational analysis through the informatics core and the diffuse large B-cell lymphoma project.
The informatics core and the DLBCL project are components of the same SCOR award.
Selected outputs · 1 coauthored publication
- The LMO2–LDB1–TAL1 complex regulates transcription networks in acute myeloid leukemia (2025) · Acknowledges LLS 7029-23/22
Coauthored acute myeloid leukemia study; the SCOR is acknowledged under the combined identifier.
Components of this program
- Core B / Core 2: Spatial, Single-cell, and Integrative Informatics and Statistics Core. Led by Christopher E. Mason; Weill Cornell subaward LLS 7029-22. Weill Cornell record
- Project 2: Genetically and epigenetically modified targets in the immune niche of diffuse large B-cell lymphoma. Led by Ari M. Melnick.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| The Immune Niche in the Development of Hematological Malignancies and Implications for Novel Therapy Blood Cancer United | Project term, center principal investigator, and the projects and cores with their leads (Project 2: Ari Melnick; Core B: Christopher Mason). | Not yet archived |
| Immune Niche SCOR, Core 2 (LLS 7029-22) Weill Cornell VIVO | The Weill Cornell core subaward, its dates and investigators. | Wayback Machine |
BAF complex deregulation in lymphoma
- Funder
- NIH / National Cancer Institute
- Program
- BAF complex deregulation in lymphoma
- Award number
- R01CA266279
- Award period
- August 2022 – July 2027 (NIH RePORTER).
- Principal investigators
- Michael R. Green (contact PI, MD Anderson Cancer Center) and Christopher E. Mason. Weill Cornell subaward: Christopher E. Mason (subaward principal investigator) and Ari M. Melnick (co-principal investigator).
- Dr. Meydan’s role
- Co-investigator
This NCI R01 investigates how BAF/SWI-SNF chromatin-remodeling defects contribute to lymphoma development and altered gene regulation. As a co-investigator, Dr. Meydan brings computational epigenomics and cell-state analysis expertise to the collaborative research. Related publications from the participating groups address ARID1A, SWI/SNF, and 3D genome organization.
Selected outputs · 4 coauthored publications · 2 resources
- SWI/SNF complexes shape 3D chromatin architecture through CTCF and cohesin (2026) · Acknowledges R01 CA266279
Dr. Meydan is co-first and co-corresponding author and led the computational analyses.
- ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors (2024) · Acknowledges R01 CA266279
Dr. Meydan is co-first author.
- SMARCA4 is a haploinsufficient B-cell lymphoma tumor suppressor (2024) · Acknowledges R01CA266279
Coauthored study of SMARCA4 loss in B-cell lymphoma.
- The LMO2–LDB1–TAL1 complex regulates transcription networks in acute myeloid leukemia (2025) · Acknowledges R01CA266279
Coauthored study of the transcriptional networks of acute myeloid leukemia.
- Nature 2026 analysis code · Study resource · archived
Analysis code for the coauthored study.
- ARID1A-related patent application · Study resource · archived
Related invention — named inventor.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| BAF complex deregulation in lymphoma, R01CA266279 NIH RePORTER | Award number, principal investigators, institution and project dates. | Wayback Machine |
| BAF complex deregulation in lymphoma (Weill Cornell subaward) Weill Cornell VIVO | Weill Cornell subaward of R01CA266279, 2022–2027, and its Weill Cornell investigators. | Wayback Machine |
| Discovery suggests new strategy against follicular lymphoma Weill Cornell Medicine Newsroom | Related ARID1A research from the collaborating laboratories. | Wayback Machine |
Cancer research and translational programs
Collaborations spanning lymphoma, leukemia, chromatin architecture, tumor immunity, and translational research.
Targeting the latency switch in EBV-associated lymphomas
- Funder
- NIH / National Cancer Institute
- Program
- Targeting Latency Switch in EBV+ Lymphomas
- Award number
- R37CA262517
- Award period
- July 2022 – June 2027 (NIH RePORTER). Held at Weill Cornell Medicine through February 2026, then transferred to NYU Grossman School of Medicine.
- Principal investigators
- Lisa Giulino Roth (principal investigator)
- Dr. Meydan’s role
- Key personnel
This NCI-funded research tests strategies to modify Epstein–Barr virus latency in lymphoma and improve the visibility of malignant cells to immune responses. Dr. Meydan contributed computational research expertise to the program’s investigation of viral gene regulation and epigenetic therapeutic strategies during his Weill Cornell participation.
Some public records end on February 28, 2026: that date closes the Weill Cornell period of the award. NIH RePORTER lists the continuation at NYU Grossman School of Medicine through June 30, 2027.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Targeting Latency Switch in EBV+ Lymphomas, R37CA262517 NIH RePORTER | Principal investigator, project dates and the 2026 change of institution. | Wayback Machine |
| R37CA262517 award detail HHS TAGGS | Award actions by fiscal year. | Wayback Machine |
| EBV-associated lymphomas Roth Lab, Weill Cornell Medicine | The research project and its aims. | Wayback Machine |
Chromatin architecture and cancer progression
- Funder
- NIH / National Cancer Institute
- Program
- The Impact of Changes in Chromatin Architecture on Cancer Phenotypes and Tumor Progression
- Award number
- P01CA229086
- Award period
- Program project from June 2019; renewed, with current project dates through March 2030 (NIH RePORTER).
- Principal investigators
- Jane A. Skok (program principal investigator, NYU Grossman School of Medicine). Project leads in the first cycle included Ari M. Melnick (Project 2, the cohesin complex in myeloid leukemia) and Iannis Aifantis.
- Dr. Meydan’s participation
- 2019–2024 (Dr. Meydan’s records).
- Dr. Meydan’s role
- Key personnel
This NCI program examines how changes in 3D chromatin architecture alter gene regulation, cell identity, and cancer progression. Dr. Meydan contributed computational genomics expertise to the collaborative research during the 2019–2024 period of his involvement.
Selected outputs · 3 coauthored publications
- SETD2 haploinsufficiency enhances AICDA mutagenesis in B-cell lymphoma (2022) · Acknowledges P01 CA229086
Coauthored study of SETD2 loss and AICDA mutagenesis in B-cell lymphoma.
- Smc3 dosage regulates B-cell transit through germinal centers (2021) · Acknowledges P01 CA229086
Coauthored study of cohesin dosage in germinal-center B cells and lymphomagenesis.
- Evolution of the epigenetic landscape in childhood B-ALL and drug resistance (2020) · Acknowledges P01 CA229086
Coauthored study of epigenetic evolution and drug resistance in childhood B-ALL.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| The impact of changes in chromatin architecture on cancer phenotypes and tumor progression, P01CA229086 NIH RePORTER | Program principal investigator, project dates, and projects and cores with their leads. | Wayback Machine |
Mechanism-based targeting of mantle cell lymphoma
- Funder
- NIH / National Cancer Institute
- Program
- Mechanism-Based Targeting of Mantle Cell Lymphoma
- Award number
- P01CA214274
- Award period
- September 2018 – August 2025 (NIH RePORTER).
- Principal investigators
- Selina Y. Chen-Kiang (program principal investigator, Weill Cornell Medicine)
- Dr. Meydan’s participation
- 2018–2024 (Dr. Meydan’s records).
- Dr. Meydan’s role
- Key personnel
This NCI program brought together molecular, functional-genomic, and statistical research to define dependencies and therapeutic opportunities in mantle cell lymphoma, including CDK4, FOXO and chromatin remodeling, and PRMT5. Dr. Meydan contributed computational biology expertise as key personnel in this multi-investigator translational research effort.
Selected outputs · 4 coauthored publications
- PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma (2023) · Acknowledges P01 CA214274
Coauthored mantle cell lymphoma study.
- The novel immunocompetent Eμ-SOX11CCND1 mouse model resembles human mantle cell lymphoma (2025) · Acknowledges P01CA214274
Coauthored study establishing an immunocompetent mantle cell lymphoma mouse model.
- ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors (2024) · Acknowledges P01 CA214274
Coauthored B-cell lymphoma study; Dr. Meydan is co-first author.
- Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis (2024) · Acknowledges P01CA214274
Coauthored lymphoma study.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Mechanism-Based Targeting of Mantle Cell Lymphoma, P01CA214274 NIH RePORTER | Program principal investigator, project dates, and projects and cores with their leads. | Wayback Machine |
Targeting enhancer dysfunction in hematological malignancy
- Funder
- Leukemia & Lymphoma Society (now Blood Cancer United)
- Program
- Targeting Enhancer Dysfunction in Hematological Malignancy — Specialized Center of Research (SCOR)
- Award number
- LLS SCOR 7021-20
- Award period
- October 2019 – September 2024 (Dr. Meydan’s records).
- Principal investigators
- Jonathan D. Licht (center principal investigator); collaborators include Ari M. Melnick.
- Dr. Meydan’s role
- Key personnel (Core B)
This LLS Specialized Center of Research investigated enhancer dysfunction and epigenetic mechanisms in blood cancers. As key personnel in Core B, Dr. Meydan contributed computational research expertise to the center’s studies of dysregulated gene expression and therapeutic opportunities.
This is the award cycle before the 2024–2029 Blood Cancer United SCOR led by Dr. Licht (listed under Recent and multi-year funded programs). They are separate entries.
Selected outputs · 3 coauthored publications
- SWI/SNF complexes shape 3D chromatin architecture through CTCF and cohesin (2026) · Acknowledges LLS SCOR 7021-20
Dr. Meydan is co-first and co-corresponding author.
- ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors (2024) · Acknowledges LLS SCOR 7021-20
Dr. Meydan is co-first author.
- Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis (2024) · Acknowledges LLS SCOR 7021-20
Coauthored lymphoma study.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Jonathan Licht, MD Blood Cancer United | Dr. Licht as principal investigator of a continuing LLS SCOR program. | Not yet archived |
| SWI/SNF complexes, CTCF and 3D genome organization (Nature, 2026) Nature | Funding statement: Ari Melnick supported by LLS SCOR 7021-20. Dr. Meydan is a co-first and co-corresponding author of the paper. | Wayback Machine |
Epigenetics and DNA damage responses in hematologic disorders
- Funder
- Leukemia & Lymphoma Society (now Blood Cancer United)
- Program
- Therapeutic Implications of Altered Epigenetics and DNA Damage Responses in Hematologic Disorders — Specialized Center of Research (SCOR)
- Award number
- LLS 9238-16
- Award period
- 2016–2022 (program period stated by Blood Cancer United).
- Principal investigators
- Tak W. Mak (center principal investigator)
- Dr. Meydan’s participation
- 2016–2021 (Dr. Meydan’s records).
- Dr. Meydan’s role
- Key personnel (Core B)
This LLS SCOR examined the interaction of epigenetic abnormalities and DNA-damage responses in hematologic malignancies. Dr. Meydan contributed to its computational research core as key personnel, building experience across mechanistic cancer epigenomics and multi-investigator therapeutic research. The program preceded the 2022–2027 immune-niche SCOR led by Dr. Mak.
Selected outputs · 2 coauthored publications
- ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors (2024) · Acknowledges LLS 9238-16
Dr. Meydan is co-first author.
- The Space Omics and Medical Atlas (SOMA) and international astronaut biobank (2024) · Acknowledges LLS 9238-16
Dr. Meydan is co-corresponding author.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| The Immune Niche in the Development of Hematological Malignancies (lay abstract) Blood Cancer United | States that Dr. Mak’s team held a previous LLS SCOR from 2016 to 2022. | Not yet archived |
| SOMA Browser — funding acknowledgments Weill Cornell Medicine | Lists LLS 9238-16 among the grants acknowledged by the SOMA Browser, whose code and visualizations are by Dr. Meydan. | Wayback Machine |
| Circulating miRNA spaceflight signature reveals targets for countermeasure development (Cell Reports, 2020) Cell Reports | A paper coauthored by Dr. Meydan whose funding statement lists “LLS 9238-16, Mak”. | Not yet archived |
Chromatin mechanisms and epigenetic targeting in hematological malignancies
- Funder
- Leukemia & Lymphoma Society (now Blood Cancer United)
- Program
- Marshall A. Lichtman Specialized Center of Research (SCOR) led by Jonathan Licht, 2012 award cycle (project title in Dr. Meydan’s records: Chromatin Mechanisms and Epigenetic Targeting in Hematological Malignancies)
- Award period
- Five-year award announced by LLS in September 2012.
- Principal investigators
- Jonathan D. Licht (center principal investigator, then at Northwestern University), with co-investigators at Rockefeller University, Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center and the University of Michigan.
- Dr. Meydan’s participation
- 2015–2017 (Dr. Meydan’s records).
- Dr. Meydan’s role
- Key personnel
This earlier LLS SCOR brought together investigators studying chromatin regulation and epigenetic targets in leukemia, lymphoma, and myeloma. Dr. Meydan served as key personnel within the Weill Cornell collaboration during the later years of this award cycle.
Dr. Licht’s SCOR program has been funded in successive award cycles. The 2019–2024 and 2024–2029 cycles are separate entries.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Licht receives grant for blood cancer research Northwestern University Feinberg School of Medicine | The 2012 SCOR award to Dr. Licht, its five-year term and its co-investigator institutions, including Weill Cornell. | Wayback Machine |
| Licht Lab news (reproduces the LLS press release of September 5, 2012) Licht Lab, OpenWetWare | LLS’s announcement of the four 2012 SCOR awards and the scientific aims of Dr. Licht’s center. | Wayback Machine |
Dietary regulation of cancer immunity
- Funder
- Starr Cancer Consortium (The Starr Foundation)
- Program
- Dietary regulation of cancer immunity — Thirteenth Starr Cancer Consortium Grant Competition
- Award number
- I13-0052
- Award period
- Awarded in the consortium’s thirteenth grant competition, listed on the consortium’s site by December 2019.
- Principal investigators
- Semir Beyaz (principal investigator, Cold Spring Harbor Laboratory); co-principal investigators Christopher E. Mason (Weill Cornell Medicine) and Kıvanç Birsoy (The Rockefeller University).
- Dr. Meydan’s participation
- 2020–2021 (Dr. Meydan’s records).
- Dr. Meydan’s role
- Co-investigator
This Starr Cancer Consortium project linked nutrition, immune responses, and cancer biology across Cold Spring Harbor Laboratory, Weill Cornell Medicine, and The Rockefeller University. As a co-investigator, Dr. Meydan contributed computational and multi-omic research expertise. Published studies he coauthored acknowledge support from this award.
Selected outputs · 4 coauthored publications · 3 resources
- Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal (preprint) (2026) · Acknowledges I13-0052
bioRxiv preprint; Dr. Meydan is co-corresponding author, credited with data curation, formal analysis, software, visualization, supervision, and writing.
- SETD2 haploinsufficiency enhances AICDA mutagenesis in B-cell lymphoma (2022) · Acknowledges I13-0052
Coauthored B-cell lymphoma study.
- Smc3 dosage regulates B-cell transit through germinal centers (2021) · Acknowledges I13-0052
Coauthored study of cohesin dosage in germinal-center B cells.
- Haplotype diversity and sequence heterogeneity of human telomeres (2021) · Acknowledges I13-0052
Coauthored genome-assembly study of human telomeres.
- Diet–microbiome multi-omics explorer · Study resource · archived
Interactive explorer for the diet multi-omics data, hosted by the study team.
- Diet study analysis code and metadata · Study resource · archived
Analysis scripts and data manifests for the diet study, from the study team.
- Diet study multi-omics dataset · Study resource · archived
Multi-omics dataset listed in the preprint’s data-availability statement.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Thirteenth Starr Cancer Consortium Grant Competition Starr Cancer Consortium | The project, its principal investigator and co-principal investigators. | Wayback Machine |
| Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis (Cell Stem Cell, 2021) Cell Stem Cell | Research from the Beyaz laboratory supported by I13-0052. | Not yet archived |
| Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation (Nature Immunology, 2021) Nature Immunology | A paper coauthored by Dr. Meydan that acknowledges Starr Cancer Consortium I13-0052. | Not yet archived |
| Haplotype diversity and sequence heterogeneity of human telomeres (Genome Research, 2021) Genome Research | A paper coauthored by Dr. Meydan that acknowledges STARR I13-0052. | Not yet archived |
ECOG-ACRIN Integrated Leukemia Translational Science Center
- Funder
- NIH / National Cancer Institute
- Program
- ECOG-ACRIN Integrated Leukemia Translational Science Center (LTSC)
- Award number
- UG1CA233332
- Award period
- March 2019 – February 2026 (NIH RePORTER). The center was established in 2019.
- Principal investigators
- Ross L. Levine and Omar Abdel-Wahab (contact PIs, Memorial Sloan Kettering Cancer Center), with Ari M. Melnick, Adolfo A. Ferrando and Sheng Cai.
- Dr. Meydan’s role
- Key personnel
The NCI-supported ECOG-ACRIN Leukemia Integrated Translational Science Center connects clinical leukemia studies with molecular profiling, biomarker research, and analytical resources. Dr. Meydan contributed computational expertise as key personnel in the associated collaborative translational research.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| ECOG-ACRIN Integrated Leukemia Translational Science Center, UG1CA233332 NIH RePORTER | Award number, principal investigators, institution and project dates. | Wayback Machine |
| Leukemia Integrated Translational Science Center ECOG-ACRIN Cancer Research Group | The center’s purpose and establishment in 2019. | Wayback Machine |
| UG1CA233332 award detail HHS TAGGS | Award actions by fiscal year. | Wayback Machine |
Microbiome, infection, and spatial profiling
Research connecting computational analysis to microbial diagnostics and tissue-resolved cancer biology.
Urinary cell-free DNA to monitor infection after kidney transplantation
- Funder
- NIH / National Institute of Allergy and Infectious Diseases
- Program
- Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantation
- Award number
- R01AI151059
- Award period
- March 2020 – February 2026, including a no-cost extension (NIH RePORTER).
- Principal investigators
- Iwijn De Vlaminck (contact PI, Cornell University), Christopher E. Mason and Darshana Dadhania (Weill Cornell Medicine)
- Dr. Meydan’s participation
- 2020–2025 (Dr. Meydan’s records).
- Dr. Meydan’s role
- Key personnel
This NIH-supported Cornell–Weill Cornell collaboration investigated metagenomic profiling of urinary cell-free DNA for infection monitoring after kidney transplantation. As key personnel, Dr. Meydan contributed computational and molecular-data expertise to research on noninvasive microbial diagnostics.
Selected outputs · 2 coauthored publications
- Improved gastrointestinal health for irritable bowel syndrome with metagenome-guided interventions (2020) · Acknowledges R01AI151059
Co-first-authored study of metagenome-guided interventions in irritable bowel syndrome.
- Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19 (2021) · Acknowledges R01AI151059
Coauthored study of IL-1β and IL-6 transcriptional response modules in COVID-19.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Metagenomic profiling of urinary cell-free DNA…, R01AI151059 NIH RePORTER | Award number, principal investigators, institution and project dates. | Wayback Machine |
| Intercampus team to develop post-transplant UTI diagnosis Cornell Chronicle | The 2020 award announcement and its investigators. | Wayback Machine |
| Intercampus collaboration awarded grant to develop method for diagnosing urinary tract infections Weill Cornell Medicine Research | Weill Cornell announcement of the award. | Wayback Machine |
A spatially resolved molecular atlas of colorectal cancer
- Funder
- Gastro-Intestinal Research Foundation (CA CURE)
- Program
- Colorectal Cancer (CRC) Cellular Heterogeneity, Metastasis, and a Spatially-resolved Molecular Atlas for the Colon
- Award period
- 2022–2024 (Dr. Meydan’s participation period).
- Principal investigators
- Christopher E. Mason (principal investigator)
- Dr. Meydan’s role
- Key personnel
This Gastro-Intestinal Research Foundation project applied spatially resolved RNA and protein profiling to colorectal cancer heterogeneity, tissue organization, and metastasis. Dr. Meydan contributed computational expertise as key personnel, extending his spatial-omics research into solid-tumor biology.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| CA CURE research grants Gastro-Intestinal Research Foundation | The funded project and its lead investigator. | Wayback Machine |
Spaceflight and interdisciplinary genomics
NASA-supported molecular spaceflight research and earlier integrative genomics programs.
Spatiotemporal mapping of spaceflight effects on heart and brain
- Funder
- NASA Space Biology
- Program
- Spatiotemporal Mapping of the Impact of Spaceflight on the Heart and Brain
- Award number
- 80NSSC22K0254
- Award period
- December 2021 – November 2024 (NASA Task Book).
- Principal investigators
- Christopher E. Mason (principal investigator); co-investigators Sylvain Costes and Jonathan Galazka (NASA Ames) and Stefania Giacomello (KTH)
- Dr. Meydan’s role
- Key personnel
This NASA program investigated the molecular effects of spaceflight in heart and brain using spatial transcriptomics, single-cell profiling, and integrative analysis. As key personnel, Dr. Meydan contributed computational research expertise to the study of tissue- and cell-specific responses.
Selected outputs · 3 coauthored publications · 1 resource
- Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight (2024) · Acknowledges 80NSSC22K0254
Coauthored spatial multi-omics study of skin samples from spaceflight.
- Single-cell multi-ome and immune profiles of the Inspiration4 crew (2024) · Acknowledges 80NSSC22K0254
Coauthored single-cell multi-ome study of the Inspiration4 crew.
- The Space Omics and Medical Atlas (SOMA) and international astronaut biobank (2024) · Acknowledges 80NSSC22K0254
Dr. Meydan is co-corresponding author.
- SOMA Browser · Study resource · archived
Dr. Meydan wrote the browser’s code and visualizations; the site acknowledges this award.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Task Book project record, 80NSSC22K0254 NASA Task Book | Project, principal investigator and co-investigators, dates, scientific plan, and a bibliography that includes papers coauthored by Dr. Meydan. | Wayback Machine |
The noncoding genome and epigenome in astronauts
- Funder
- NASA Human Research Program
- Program
- An Integrated Framework for Characterization of the Noncoding Genome and Epigenome in Astronauts
- Award number
- NNX17AB26G
- Award period
- October 26, 2016 – October 25, 2018 (NASA Task Book).
- Principal investigators
- Christopher E. Mason (principal investigator); co-investigator Michael Snyder (Stanford University)
- Dr. Meydan’s role
- Key personnel
This NASA Human Research Program award supported analysis of noncoding genomic and epigenomic changes during human spaceflight. Dr. Meydan contributed computational genomics expertise as key personnel, connecting epigenome analysis with longitudinal research on astronaut molecular responses.
Selected outputs · 3 coauthored publications · 1 resource
- Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight (2024) · Acknowledges NNX17AB26G
Coauthored spatial multi-omics study of skin samples from spaceflight.
- Single-cell multi-ome and immune profiles of the Inspiration4 crew (2024) · Acknowledges NNX17AB26G
Coauthored single-cell multi-ome study of the Inspiration4 crew.
- The Space Omics and Medical Atlas (SOMA) and international astronaut biobank (2024) · Acknowledges NNX17AB26G
Dr. Meydan is co-corresponding author.
- SOMA Browser · Study resource · archived
Dr. Meydan wrote the browser’s code and visualizations; the site lists NNX17AB26G among its support.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Task Book project record, NNX17AB26G NASA Task Book | Project title, principal investigator and co-investigator, grant number, start and end dates (NASA Human Research Program). | Wayback Machine |
| SOMA Browser — funding acknowledgments Weill Cornell Medicine | Acknowledges NASA NNX17AB26G among the grants supporting the SOMA data resource, whose code and visualizations are by Dr. Meydan. | Wayback Machine |
Epigenome interactions in complex neurogenetic disorders
- Funder
- NIH / National Institute of Neurological Disorders and Stroke
- Program
- Epigenome Interactions in Complex Neurogenetic Disorders
- Award number
- R01NS076465
- Award period
- September 2011 – May 2017 (NIH RePORTER).
- Principal investigators
- M. Elizabeth Ross (contact PI) and Christopher E. Mason, Weill Cornell Medicine
- Dr. Meydan’s role
- Key personnel
This NINDS-funded project studied interactions between genetic and epigenetic variation in complex neurogenetic disorders. Dr. Meydan contributed genomic analysis and computational research expertise as key personnel, reflecting an earlier phase of his work integrating heterogeneous molecular data.
Selected outputs · 2 coauthored publications
- Combination targeted therapy in IDH2- and TET2-mutant AML (2017) · Acknowledges R01NS076465
Co-first-authored Cancer Discovery study of combination targeted therapy in IDH2- and TET2-mutant AML.
- Haplotype diversity and sequence heterogeneity of human telomeres (2021) · Acknowledges R01NS076465
Coauthored genome-assembly study of human telomeres.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| Epigenome Interactions in Complex Neurogenetic Disorders, R01NS076465 NIH RePORTER | Award number, principal investigators and project dates. | Wayback Machine |
| Grant record and project abstract OpenAlex | Indexed award record and abstract. | Wayback Machine |
| Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome (Nature Methods, 2015) Nature Methods | A paper coauthored by Dr. Meydan that acknowledges NS076465 (to C.E. Mason). | Wayback Machine |
Earlier international research programs
Selected earlier collaborative research outside the current lab’s central disease areas.
Show earlier project outside the current research focus
JADE: transnational research clusters for independent living of older adults
- Funder
- European Commission, Seventh Framework Programme (Regions of Knowledge)
- Program
- JADE — Joining innovative Approaches for the integration and Development of transnational knowledge of clusters policies related to independent of Elderly
- Award number
- Grant agreement 266422
- Award period
- February 2011 – January 2014 (CORDIS).
- Principal investigators
- Coordinated by Sviluppo Europa Marche (Italy), with 41 participating organizations including Sabancı University (Türkiye)
- Dr. Meydan’s role
- Key personnel
JADE was a European Commission-supported collaboration on research-driven innovation for independent living among older adults. Dr. Meydan served as key personnel in the Sabancı University-associated work during an earlier stage of his research career.
Sources
| Source | What it documents | Archived copy |
|---|---|---|
| JADE, grant agreement 266422 European Commission CORDIS | Project, programme, dates and participating organizations. | Wayback Machine |
Content reviewed 2026-10-31.
